Rituximab is used in the treatment of non-Hodgkin lymphoma (NHL), rheumatoid arthritis, blood cancer (chronic lymphocytic leukemia), granulomatosis with polyangiitis, and microscopic polyangiitis.
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Relyto 500mg/50ml Infusion, classified as a monoclonal antibody, is employed for the treatment of conditions such as non-Hodgkin’s disease and chronic lymphocytic leukaemia. Additionally, it finds application in managing rheumatoid arthritis when used in conjunction with methotrexate, as well as granulomatosis when combined with glucocorticoids. It is also utilized to address Pemphigus Vulgaris (PV) and mature B-cell acute leukaemia (B-AL).
Relying on Rituximab as its active ingredient, Relyto 500mg/50ml Infusion hinders DNA and RNA transcription, crucial processes for the growth of cancer cells. This action aids in preventing the proliferation and spread of both cancerous and non-cancerous cells. Furthermore, Relyto 500mg/50ml Infusion intervenes in the immune system process that triggers inflammation in joint tissues, mitigating pain and inflammation, and impeding joint damage and disease progression over time.
While the administration of Relyto 500mg/50ml Infusion by a trained healthcare professional is essential due to its parenteral nature, certain side effects may be experienced. These can include pale skin, painful urination, night sweats, flushing, back pain, nausea, vomiting, diarrhoea, stomach pain, mouth sores, peeling of skin, and pain at the injection site. Although these side effects generally resolve over time and may not necessitate medical attention, persistent or worsening symptoms should be promptly discussed with a doctor.
Individuals with allergies to Relyto 500mg/50ml Infusion components should avoid its use. Comprehensive disclosure of medical history, including current medications, liver/kidney disease, hepatitis B virus infection, cardiac disorders, active infections, or gastrointestinal issues, is crucial for ruling out potential side effects or interactions. Monitoring for complications such as bowel obstruction, perforation, Hepatitis B reactivation, cardiac arrhythmias, tumour lysis syndrome, and angina is vital throughout the treatment duration. Pregnant or breastfeeding individuals should inform their healthcare provider for appropriate guidance.
Avoid consumption of alcohol while receiving Relyto 500mg/50ml Infusion as it may make you feel drowsier.
Relyto 500mg/50ml Infusion may be unsafe to use during pregnancy.
Animal studies have shown adverse effects on the fetus, however, there are limited human studies. The benefits from use in pregnant women may be acceptable despite the risks. Please consult your doctor.
Human and animal studies are not available. Please consult your doctor.
There is no data available. Please consult a doctor before consuming the drug.
There is no data available. Please consult the doctor before consuming the drug.
There is no data available. Please consult a doctor before consuming the drug.
Relyto 500mg/50ml Infusion operates as a monoclonal antibody, exerting its therapeutic effects through two main mechanisms:
Destruction of Immune Cells (B-cells): Relyto 500mg/50ml Infusion targets and destroys B-cells, a type of immune cell. This action is particularly relevant in cancer treatment, as it aims to curb the formation and proliferation of cancer cells triggered by B-cells.
Reduction in Chemical Production: The medication also plays a role in diminishing the production of specific chemicals within the body. These include rheumatoid factors, T-cells, and cytokines. By modulating these chemical signals, Relyto 500mg/50ml Infusion addresses inflammation, pain, and swelling. Consequently, it proves beneficial in the treatment of various autoimmune diseases, such as rheumatoid arthritis, where an overactive immune response contributes to joint-related symptoms.
In summary, Relyto 500mg/50ml Infusion's dual mechanism involves targeting and eliminating specific immune cells associated with cancer formation while concurrently regulating the production of inflammatory chemicals to alleviate symptoms of autoimmune diseases.
Common Side Effects:
Uncommon Side Effects:
Rare Side Effects: Contact your doctor immediately if you experience any of the following:
These indications highlight the diverse applications of Relyto 500mg/50ml Infusion in treating various conditions, including lymphomas, leukemia, and autoimmune diseases.
Non-Hodgkin Lymphoma (NHL):
Chronic Lymphocytic Leukemia (CLL):
Granulomatous Polyangiitis (GPA) and Microscopic Polyangiitis (MPA):
Rituximab, present in Relyto 500mg/50ml Infusion, is a chimeric monoclonal antibody that exerts its therapeutic effects through various mechanisms:
CD20 Antigen Binding:
Complement-Dependent B-Cell Cytotoxicity (CDC):
Antibody-Dependent Cellular Toxicity (ADCC):
Pharmacokinetics:
Understanding these mechanisms provides insight into how Relyto 500mg/50ml Infusion modulates the immune response to target and eliminate specific cells, contributing to its therapeutic efficacy in conditions such as lymphomas and autoimmune diseases.
Adult Dose:
Child Dose:
These dosages are specific to each condition and should be administered under the guidance of a healthcare professional. Patients must follow the prescribed regimen and consult their doctor for any concerns or adjustments.
Reconstitution:
IV Administration:
First IV Infusion Rate:
Subsequent IV Infusions (90 minutes):
It's important to inform your doctor about all the medications you are currently taking before receiving Relyto 500mg/50ml Infusion.
Medicines used to treat high blood pressure:
Medicines that can suppress immune functions:
Other anticancer medicines:
Always follow your doctor's recommendations and inform them about any changes in your medication regimen.
Pregnancy group C. Animal studies have shown adverse effects on the fetus (teratogenic or embryotoxic or others) and there are no controlled studies in women or no studies. in women and animals. The drug should be used only if there is a potential benefit to the fetus.
Store between 2-8° C.
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